Have you heard of CRISPR? You may even have heard the full transcript of the term: short palindromic repeats regularly spaced bands (Clustered Regularly Interspaced Short Palindromic Repeats). Or heard. If not, you will have very soon to remember this acronym. It is a kind of cause and effect of the revolution. It is the most powerful tool for editing the genome of all that ever existed.
In fact, CRISPR allows anyone to edit the DNA of an organism, enable or disable certain features and introduces a brand new one.
In the past, editing DNA was extremely difficult, time consuming and inaccurate. CRISPR is a completely opposite: cheap, easy and accurate.
It consists of a "guide" RNA, which can detect a specific piece of DNA, and skalpelepodobnogo enzyme called CAS9, which is exactly this part of the cuts. It can also be fitted to replace the DNA portion to fill that has been cut out.
Over the past few years, there was a flurry of research CRISPR, because the scientific community is trying to determine the limits of this technique - which seem limitless - as well as hone their understanding of how it can and should be used.
This part of science seems quite fantastic, but it can affect the lives of people around the world.
Here are several options CRISPR challenge the problems of people in the coming years.
Infectious diseases
Many infectious diseases are choosing a roundabout way, getting to the person. Lyme disease, for example, is caused by bacteria that are picked up ticks Ixodida (in most cases), and after landing on mice and bite them. Then the tick bites a human, causing fatigue, illness, the need for antibiotics and a significant reduction in quality of life.
Malaria comes about as transmitted parasites loved us all: mosquitoes.
From 300 to 500 million people are infected and more than 1 million, primarily children under 5 years die of malaria each year.
With CRISPR scientists will be able to cut out the genes that allow mosquitoes carry the parasite that carries malaria, and then make sure that this change will take place through the generations, and take hold of the whole population. If successful, this will put an end to malaria, which kills millions of people and leaving families without a breadwinner, that will begin the fight against poverty.
Genetic diseases
Very many diseases and abnormalities are inherited from cystic fibrosis to Down syndrome, from sickle cell anemia to mental disorders and myopia.
Other diseases arise from random mutations in the human genome. CRISPR may be able to fix the human genome so that he will never suffer from terrible diseases that appear from time to time.
Particularly interesting prospect for the poor people, who often lack the resources to fully recover from the disease. Moreover, once the disease will be excluded from the human genome, it will be protected from future generations. It is the most effective way to protect society for a long time.
Cancer
One of the main enemies of human life, cancer affects people from all walks of life. But the main risk factor is the poor man in poverty under stress, is located in an environment with increased toxicity, which increases the chance of developing cancer. He also hardly get timely treatment and unlikely to be able to pay for it in full.
Cancer is known to be unpredictable and difficult to control. Everyone, it seems, has its own type of cancer that can challenge the procedures appropriate for the treatment of others.
With CRISPR may be possible to develop "therapeutic road map" for cancer of each individual and accurate prediction and an indication of possible mutations that may occur. In theory, this makes all of the cancer can be treated.
Agriculture and food
Food, agricultural industry and the scientific community was able to bury all the benefits of GMOs. And why do they insist on such a strange name - genetically modified organisms - I'll never know.
When tested, and correct information in the beginning of the fall roundup, people were filled with fear of GMOs; It left too little room for important information that could affect people.
GMOs do not present any risk to humans (this is, in fact, an accelerated form of natural selection), and will be critical in the current and future fight against food insecurity and climate change.
But while they are fighting for public recognition.
Some scientists believe that the CRISPR may be a more acceptable concept, but there are fears: it is still a complicated process, which may alarm the public.
CRISPR will not include foreign DNA in crops, but instead modifies the existing genomes, increasing their resistance to drought, bad weather, extreme heat and other conditions, as well as increase the volume of receiving nutrients.
Soybeans, potatoes, and rice has been improved. Scientists will also be able to remove allergens from food, such as peanuts. Such achievements to strengthen the control of food around the world, especially to help people living in poor conditions.
Saving trees
Trees - the best there is in the world. They allow us to live, provide us with food and generally causing pleasant emotions. However, people cut down trees billions pests also significantly hinder them. For example, higher temperatures and longer warm seasons in North America allows pine beetles to flourish. These beetles eat the pine woods throughout the western United States and Canada.
CRISPR allow scientists to eliminate certain genes that attract pests, and enable others to protect them.
Organ transplant
Last week, I ate pork. It was delicious. Like many other people, I have no problems with the absorption of pork (not every day, of course). But what if the pork is to be a part of me? Would I kind of pig?
Scientists have long wanted to use pig bodies to put an end to the eternal deficit of human organs. Usually, a person has to wait a long time until it receives available to the transplant organ.
Pig organs are similar to human, but the DNA of pigs teeming with retroviruses that infect humans after transplantation. CRISPR allow scientists to remove these viruses and, theoretically, to open the door to an abundance of safety. This can significantly reduce the black market, which operates thanks to the people living in poverty.
Antibiotics
Powerful bacteria - a terrible thing. Fears postantibioticski era only grow when the antibiotics will not be able to save us from bacterial infections.
The prevalence of superbugs is increasing every year, and the prospect of the development of more powerful antibiotics remains elusive distant. But CRISPR can greatly help the fight against antibiotic-resistant bacteria.
Water purification
783 million people worldwide do not have access to clean water. Most people get the disease from contaminated water, which can kill or leave them in a terrible state of health.
CRISPR can help in the development of enzymes that can effectively and cheaply purify water. Dissolve the tablet in water and make it clean - what better way to help poor people?
Biofuels
Humanity is desperately looking for an alternative to fossil fuels. Biofuels are considered to be ineffective: for its use required a large area, it is difficult to extract, process, and it still pollutes the atmosphere. But scientists believe that the CRISPR can significantly improve the technology of biofuels.
These are just some of the many possible uses CRISPR. The full range of possibilities is very, very great. Of course, you need to approach it is not without caution. The ethics of genome editing has to be carefully worked out at the highest level. I'm not exactly been thrilled with the fundamental change in the human genome. The idea of a significant change in the human condition scares me. But CRISPR seems tool that can help us to overcome poverty and to overcome the abyss of global inequality. And it is worth to try.